The synthetic purine reversine selectively induces cell death of cancer cells
AbstractThe synthetic purine reversine has been shown to possess a dual activity as it promotes the de‐differentiation of adult cells, including fibroblasts, into stem‐cell‐like progenitors, but it...
View ArticleClinicopathological study of 81 cases of localized and systemic scleroderma
Conclusion The features of morphea/scleroderma patients in this study are generally comparable to those published in the literature, with few differences. Clinically, plaque type morphea was the most...
View ArticleNano-titanium dioxide modulates the dermal sensitization potency of DNCB
In conclusion, our study demonstrates that administration of nano-TiO2 increases the dermalsensitization potency of DNCB, by augmenting a Th2 response, showing theimmunomodulatory abilities of NPs....
View ArticleEffect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma...
ConclusionThis study describes a new mechanism by which ROS may promote a profibrotic phenotype in SSc fibroblasts through the oxidative inactivation of PTP1B, leading to pronounced activation of...
View ArticleCytokine response in patients with chronic infections caused by...
This study aimed to describe the levels of circulating cytokine levels produced by Th lymphocytes (IFN-γ, IL-4, IL-10, IL-17A), as well as the levels of cytokines produced by monocytes/macrophages...
View ArticleSmad4 disruption accelerates keratinocyte reepithelialization in murine...
In this study, full-thickness skin wounds were made in keratinocyte-specific Smad4 knockout and the control mice. Link: Smad4 disruption accelerates keratinocyte reepithelialization in murine cutaneous...
View ArticleHuman periodontal ligament cells reaction on a novel hydroxyapatite–collagen...
ConclusionsThis study proved that HA‐PADM scaffold is ‐biocompatible for hPDL cells. The cells were able to proliferate and migrate into the scaffold. Go here to see the original: Human periodontal...
View ArticleHealing rates for challenging rotator cuff tears utilizing an acellular human...
Conclusions: This study presents a safe and effective technique that may help improve the healing rates of large, massive, and revision rotator cuff tears with the use of an acellular human dermal...
View ArticleEstradiol Protects Hyaluronan/Versican Matrix from UVB [Cell Biology]
Hyaluronan (HA) and versican are key components of the dermis and are responsive to ultraviolet (UV)B-induced remodeling. The aim of this study was to explore the molecular mechanisms mediating the...
View ArticlePlastic Surgery – Study Shows Positive Mental Benefits of Cosmetic Surgery –...
Plastic Surgery – Study Shows Positive Mental Benefits of Cosmetic Surgery SBWire (press release) Epione Beverly Hills has been a leader in minimally-invasive aesthetic medicine and laser technology....
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